Vitiligo is an autoimmune disorder characterized by the destruction or abnormal function of melanocytes (pigment-producing cells).

  • It is known to affect 1-2% of the total world’s population.
  • It presents as white spots on skin and mucosa and silvery grey hair on the scalp. Vitiligo can be either stable (not spreading or increasing) or progressive.
  • Vitiligo is known to affect the quality of life and causes immense psychological stress in patients.

Clinically Vitiligo can be classified as:

  1. Segmental type – This can affect one or multiple segments of the body.
  2. Non-segmental type – Which can be acrofacial (affecting face, head, perioral, hands, and feet), mucosal (genital and oral mucosa involvement), generalized (any part of the body), universal (>80-90% body involvement), mixed (involvement of segmental and non-segmental type).
  3. Unclassified or indeterminate – Can be focal (isolated spots are seen without segmental distribution) or mucosal (where only one mucosa is involved).

The exact etiopathogenesis of vitiligo is still unknown, but several theories have been proposed:

  1. Autoimmune Theory
  2. Adhesion Defect Theory
  3. Neural Defect
  4. Vitiligo’s Biochemical Theory
  5. Intrinsic Theory
  6. Viral Theory
  7. Integrated Theory

Estique Clinic, the best skin clinic in Gurgaon for vitiligo treatment in Gurgaon, have specialists who can better understand the main pathways involved in vitiligo onset will help in the formation of the optimal treatment plan which would stabilize melanocytes, suppress autoimmune response and increase regeneration of melanocytes and stimulate their migration from surrounding skin and adnexa.

Management of Vitiligo can be:

  1. Pharmacological – Which includes the use of medicated creams and systemic agents.
  2. Physical Therapy – Use of UV radiation.
  3. PUVA Light Therapy – Should be done under supervision. It Involves the use of UVA and the photosensitizing drug, psoralen.
  4. NBUVB Therapy – Use of narrowband UVB (311 nm) to restore skin colour, no need for oral psoralens, safe, minimum side effects.
  5. Excimer LASER – Use of coherent and monochromatic light, 308 nm to restore colour.
  6. Surgical modalities – They are used when the vitiligo is stable. Methods used are Split-thickness skin grafting and Melanocyte transfer.


Medical and Cosmetic Dermatologist and well renowned as the Best Dermatologist in Gurgaon, has formerly practised in prestigious Hospitals such as VMMC & Safdarjung Hospital (New Delhi) and All India Institute of Medical Sciences (AIIMS, New Delhi). She has done teo superspecializtions - Fellowship in LASERS and Dermatology from National Skin Centre , Singapore and Fellowship in Aesthetic Dermatology from Bangkok. She has a total experience of 11 years and has treated over 20000 patients.
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