Urticaria is a relatively common heterogeneous skin disorder that may be acute or chronic. It is difficult to determine, especially when it becomes chronic. We, Estique Clinic, have the best dermatologists in Gurgaon who can give the best treatments for Urticaria
There are two types of Urticaria to classify such as:
A. Spontaneous Urticaria – It is the most common type of urticaria The symptoms and the signs of illness will be visible such as wheals, angioedema, and itchiness. According to the duration, spontaneous urticaria classified into two types such as: –
B. Inducible urticaria – It is also known as chronic physical urticaria which occur when triggered by specific physical stimuli.
Pruritus(Itching) is the most predominate symptom. Other characteristic signs include wheals and flares that vary in size, with individual wheals usually resolving within 24 hours without residual hyperpigmentation.
Pathogenesis: Acute or chronic urticaria may occur as a result of mast cell and basophil release of bioactive mediators, such as histamine and leukotrienes, after activation of either the innate or adaptive immune system.
Therefore, activation of mast cells by particular IgE, IgG or IgM antibody results urticaria activates the classical complement pathway. Other mediators (neuropeptides such as substance P, calcitonin gene-related peptide and neurokinin A) and medications such as opiates can also activate mast cells or basophils through specific receptors and for cyclooxygenase inhibitors (i.e., ASA, NSAIDS) to induce hives through non-IgE mediated pathways.
Treatment lies in removing the source of allergy. Since common causes of acute urticaria include infection and food allergy, investigation for these underlying causes should be guided by the history and physical examination. Detailed evaluation needs to be done for patients with chronic urticaria.
Antihistamines form the baseline for management. Newer treatment options include the usage of Omalizumab.
Urticaria is an autoimmune disease. In response to certain antigens (intruders) there is mast cell degranulation. These mast cells on activation release histamine and they also encourage other cells to get activated. Histamine production leads to hives formation.
Less commonly, urticaria may precede a severe allergic rection known as anaphylaxis. In anaphylaxis, there are hives and angioedema, difficulty in breathing, lightheadedness, rapid or irregular heartbeat, stomach cramps, nausea, vomiting, diarrhea.
If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, asphyxiation and death.
I found Dr Neha to be a sound, reassuring and helpful practitioner. I had gone to her for an Urticaria, and had such a good experience that I decided to get the treatment done from her as well. Highly recommend her.
I was suffering from Urticaria from long time and had visited several doctors but there was no relief. However, after meeting Doctor Neha and taking the medication, I could see changes on my skin. All thanks to Doctor Neha