Keloids or hypertrophic scars can be caused by dermal injury or irritation, trauma, insect bite, burn scars, scars from surgery, skin piercing, acne scars, vaccination, folliculitis, herpes zoster infection and chicken pox. To be precise, the injuries caused to the reticular dermis result in keloidal and hypertrophic scarring. The injury will be followed by inflammation of the healing wound. Therefore, the reticular layer of keloids consists of increased numbers of fibroblasts, newly formed blood vessels, collagen deposits and pro inflammatory factors.
- Intralesional Corticosteroids is the first line of treatment modality.
- Other modalities include Retinoids, 5-FU, Silicone gel and Cryotherapy.