Urticaria is a relatively common heterogeneous skin disorder that may be acute or chronic. It is difficult to determine, especially when it becomes chronic. We, Estique Clinic, have the best dermatologists in Gurgaon who can give the best treatments for Urticaria
There are two types of Urticaria to classify such as:
A. Spontaneous Urticaria – It is the most common type of urticaria The symptoms and the signs of illness will be visible such as wheals, angioedema, and itchiness. According to the duration, spontaneous urticaria classified into two types such as: –
- Acute Spontaneous urticaria – It is characterized by spontaneously according wheals for at less than 6 weeks.
- Chronic urticaria – It is characterized by spontaneously occurring wheals and itchiness for at least 2 days per week for a period of 6 weeks or more.
B. Inducible urticaria – It is also known as chronic physical urticaria which occur when triggered by specific physical stimuli.
Pruritus(Itching) is the most predominate symptom. Other characteristic signs include wheals and flares that vary in size, with individual wheals usually resolving within 24 hours without residual hyperpigmentation.
Pathogenesis: Acute or chronic urticaria may occur as a result of mast cell and basophil release of bioactive mediators, such as histamine and leukotrienes, after activation of either the innate or adaptive immune system.
Therefore, activation of mast cells by particular IgE, IgG or IgM antibody results urticaria activates the classical complement pathway. Other mediators (neuropeptides such as substance P, calcitonin gene-related peptide and neurokinin A) and medications such as opiates can also activate mast cells or basophils through specific receptors and for cyclooxygenase inhibitors (i.e., ASA, NSAIDS) to induce hives through non-IgE mediated pathways.
Treatment lies in removing the source of allergy. Since common causes of acute urticaria include infection and food allergy, investigation for these underlying causes should be guided by the history and physical examination. Detailed evaluation needs to be done for patients with chronic urticaria.
Antihistamines form the baseline for management. Newer treatment options include the usage of Omalizumab.
What is the main cause of urticaria?
Urticaria is an autoimmune disease. In response to certain antigens (intruders) there is mast cell degranulation. These mast cells on activation release histamine and they also encourage other cells to get activated. Histamine production leads to hives formation.
How long does urticaria last?
Urticaria can be either acute or chronic. In acute urticaria there are spontaneously occurring hives for duration less than six weeks whereas in chronic urticaria they persist beyond six weeks.
Why am I getting hives every day?
There can be multiple triggers for hives.
- Food sources like: nuts, soy, dairy, fish, eggs, tomatoes, certain food additives.
- Stress – if you are continuously stressing about hives your body will release histamine and in return you may get more hives.
- Certain medications like NSAIDS ( aspirin and ibuprofen), ACE inhibitors can cause hives.
- Infections, recent surgeries can also cause urticaria
- Presence of any other autoimmune conditions like thyroid.
Is there any cure for urticaria?
Treatment lies in removing the source of allergy. Causes of chronic urticaria are usually more difficult to find than acute urticaria. Detailed evaluation and investigations can help in figuring out the source of allergy.
What Is the best treatment of Urticaria?
Best treatment is removal of the trigger. Anti histamines form the backbone of treatment for hives. Other advanced options includes biologicals.
What are the symptoms of urticaria?
Signs and symptoms of chronic hives include:
- Batches of red or skin-colored welts (wheals), which can appear anywhere on the body
- Welts that vary in size, change shape, and appear and fade repeatedly as the reaction runs its course
- Itching, which may be severe
- Painful swelling (angioedema) of the lips, eyelids and inside the throat
Can urticaria be a sign of something serious?
Less commonly, urticaria may precede a severe allergic rection known as anaphylaxis. In anaphylaxis, there are hives and angioedema, difficulty in breathing, lightheadedness, rapid or irregular heartbeat, stomach cramps, nausea, vomiting, diarrhea.
If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, asphyxiation and death.
What foods to avoid if you have urticaria?
Fish, eggs, dairy, nuts, soy, shellfish, wheat, tomatoes, berries are certain foods that can trigger hives.
why does urticaria get worse at night?
At night, there is increase in the production of cytokines which increases inflammation whereas production of corticosteroids which reduce inflammation is decreased. Also, at night we tend to focus more on itchy skin as there are fewer distractions than during the day. The body temperature as well as blood flow increases at night warming your body. Rise in skin temperature can make you feel itchy.
How is urticaria prevented?
Keep a record of events that happen just before development of hives. This way you will be able to note your triggers. Staying away from these triggers in the future will prevent the development of hives. Read the labels of foods and medicines carefully.
I found Dr Neha to be a sound, reassuring and helpful practitioner. I had gone to her for an Urticaria, and had such a good experience that I decided to get the treatment done from her as well. Highly recommend her.
I was suffering from Urticaria from long time and had visited several doctors but there was no relief. However, after meeting Doctor Neha and taking the medication, I could see changes on my skin. All thanks to Doctor Neha